Scientist I, Synthetic Biology Job at Generate Biomedicines, Somerville, MA

  • Generate Biomedicines
  • Somerville, MA

Job Description

Generate Biomedicines seeks a Scientist in Synthetic Biology to develop pooled screening workflows for testing hundreds of thousands of protein variants in parallel. The role combines DNA library design, protein display technology, and NGS analysis to identify protein binders and modulators, with collaboration across protein sciences and machine learning teams.

Responsibilities

  • Design and implement pooled screening workflows from assay setup through data interpretation
  • Establish assay conditions, quantitative measures, and protocols for project team adoption
  • Evaluate novel hypotheses and unconventional approaches to support drug program acceleration
  • Synthesize experimental findings into recommendations and present across disciplines
  • Apply quantitative reasoning and literature review to guide experimental design decisions

Requirements

  • Strong experimental background in synthetic biology and pooled screening techniques
  • Proficiency in DNA library design and next-generation sequencing analysis
  • Experience with in vitro protein display or similar high-throughput assay methods
  • Quantitative reasoning and comfort with computational or statistical analysis
  • One position requires mammalian cell engineering and membrane protein expertise
  • Ability to communicate findings clearly to interdisciplinary teams

Job Tags

Similar Jobs

Mativ Holdings, Inc.

Sales Manager Job at Mativ Holdings, Inc.

 ...that connect, protect, and purify our world. Position Title: Sales Manager - Industrial & Optical Films location: Remote...  ...recommendations to internal and external business leaders. ~ Ability to travel 40%+, including overnight travel. Eastern US location is a plus.... 

Maison Lotus

Executive Sous Chef Job at Maison Lotus

 ...Executive Sous Chef Maison Lotus Maison Lotus in Wayne, PA is part of WIN Signature Restaurants, a family-owned hospitality group with a legacy of culinary excellence. We are seeking a career-oriented, experienced Executive Sous Chef to join our team. The They will... 

Med Source Consultants

Physician - 63109087 Job at Med Source Consultants

 ...program launching November 1, 2026 help build and shape this exciting service line from the ground up ~ Seeking four OB-GYN Hospitalists plus one OB-GYN Hospitalist Medical Director ~ Predictable 24-hour in-house shifts supporting work-life balance ~ Team structure... 

FACE FOUNDRIÉ

Advanced Practice Trainer Job at FACE FOUNDRIÉ

 ...driven by leadership, and eager to make a meaningful impact in the beauty and skincare industry. Position Overview The Traveling Trainer is a key member of the FACE FOUNDRI franchise support team, responsible for delivering hands-on training, coaching, and... 

My3Tech

Business Analyst Job at My3Tech

 ...Hello Hope you are doing great, Job Title: Business Analyst Location: Remote Contract: Long Term Job Description We are seeking an experienced Business Analyst (BA) to support a state government healthcare technology project. The ideal...